Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_474Hypothetical protein. (245 aa)    
Predicted Functional Partners:
ACPL_7884
Uncharacterized protein.
  
     0.766
ACPL_7977
Hypothetical protein.
  
     0.674
ACPL_475
Hypothetical protein.
       0.661
ACPL_3001
Antigen 84; DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
     0.641
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.633
ACPL_8113
Oxyanion-translocating ATPase.
  
     0.625
ACPL_183
Acyl-CoA dehydrogenases.
  
     0.608
ACPL_1683
Hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.587
ACPL_7391
Methionine synthase vitamin-B12 independent.
 
     0.564
ACPL_2772
Laminin subunit beta-2; Cell division initiation protein.
  
     0.543
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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