Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4772Hypothetical protein. (161 aa)    
Predicted Functional Partners:
dnaK-3
Molecular chaperone.
  
 0.848
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
   
 0.844
ACPL_8364
Putative WD repeat-containing protein; FOG: WD40 repeat.
   
 0.844
ACPL_4773
Hypothetical protein; Histone acetyltransferase HPA2 and related acetyltransferases.
       0.773
ACPL_8205
Hypothetical protein.
  
 0.753
rpsC
Small subunit ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
 0.726
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
   
 0.707
pks2A
Polyketide synthase modules and related proteins.
  
 0.706
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.697
ACPL_1165
Mov34/MPN/PAD-1 family protein; Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
    
 0.675
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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