Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4776Hypothetical protein. (509 aa)    
Predicted Functional Partners:
ACPL_5487
Acetoacetate decarboxylase.
  
     0.622
ACPL_6765
Hypothetical protein; Predicted NTPase (NACHT family).
 
     0.612
efp
Elongation factor EF-P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.610
ACPL_4585
VanZ family protein; Glycopeptide antibiotics resistance protein.
  
     0.596
ACPL_430
Leucine rich repeat variant; Predicted NTPase (NACHT family).
  
     0.538
ACPL_4501
Hypothetical protein.
  
     0.524
ACPL_4317
Hypothetical protein; Predicted HD-superfamily hydrolase.
  
     0.500
ACPL_2126
Acyl-CoA dehydrogenases.
  
    0.482
ACPL_5333
WGR domain protein.
  
     0.448
ACPL_1184
Hypothetical protein.
  
     0.435
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (18%) [HD]