STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4895Tetratricopeptide repeat protein 28; Uncharacterized protein conserved in bacteria. (892 aa)    
Predicted Functional Partners:
ACPL_4897
DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
 
    0.815
ACPL_4898
Hypothetical protein.
 
     0.798
ACPL_3179
DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
 
    0.673
ACPL_2114
Major facilitator superfamily protein.
  
     0.604
ACPL_4896
Peptidase S8/S53 subtilisin kexin sedolisin; Subtilisin-like serine proteases.
 
     0.547
ACPL_150
Disease resistance protein RPS5; Predicted ATPase.
 
  
  0.543
nhaA
Na(+)/H(+) antiporter nhaA 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.498
otsB
HAD family hydrolase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.498
afsR-4
Regulatory protein afsR; DNA-binding transcriptional activator of the SARP family.
  
  
  0.471
ACPL_3480
Guanine-specific ribonuclease N1 and T1.
  
     0.459
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.