STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4952Monoamine oxidase. (408 aa)    
Predicted Functional Partners:
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
   
 0.888
helZ
Helicase HelZ; Superfamily II DNA/RNA helicases, SNF2 family.
  
 
 0.811
ACPL_438
Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family.
  
 
 0.811
ACPL_8041
Predicted naringenin-chalcone synthase.
    
 
 0.642
ACPL_4953
Hypothetical protein.
       0.636
crtI-3
Phytoene/squalene synthetase.
  
  
 0.619
ACPL_4951
Hypothetical protein.
       0.513
ACPL_7128
Hypothetical protein.
  
     0.487
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
    0.477
ACPL_7634
DNA polymerase sliding clamp subunit (PCNA homolog).
   
    0.477
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.