holB protein (Actinoplanes sp. SE50110) - STRING interaction network

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[Homology]

Score

holB

DNA polymerase III subunit delta; ATPase involved in DNA replication. (394 aa)

Predicted Functional Partners:

ACPL_1392

0.998

dnaN

0.995

dnaE-2

0.990

dnaQ

0.984

dnaZ

0.981

ACPL_7634

0.965

ACPL_1659

0.958

dnaE

0.898

ssb

0.880

ACPL_7611

0.863

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1392	ACPL_1659	ACPL_1392	ACPL_1659	DNA polymerase III, delta subunit.	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	0.961
ACPL_1392	ACPL_7611	ACPL_1392	ACPL_7611	DNA polymerase III, delta subunit.	Superfamily I DNA and RNA helicases.	0.867
ACPL_1392	ACPL_7634	ACPL_1392	ACPL_7634	DNA polymerase III, delta subunit.	DNA polymerase sliding clamp subunit (PCNA homolog).	0.969
ACPL_1392	dnaE	ACPL_1392	ACPL_1740	DNA polymerase III, delta subunit.	DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.947
ACPL_1392	dnaE-2	ACPL_1392	ACPL_1776	DNA polymerase III, delta subunit.	DNA polymerase III, alpha subunit.	0.994
ACPL_1392	dnaN	ACPL_1392	ACPL_117	DNA polymerase III, delta subunit.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.997
ACPL_1392	dnaQ	ACPL_1392	ACPL_6692	DNA polymerase III, delta subunit.	DNA polymerase III, alpha subunit (gram-positive type).	0.986
ACPL_1392	dnaZ	ACPL_1392	ACPL_8134	DNA polymerase III, delta subunit.	DNA polymerase III, gamma/tau subunits.	0.997
ACPL_1392	holB	ACPL_1392	ACPL_496	DNA polymerase III, delta subunit.	DNA polymerase III subunit delta; ATPase involved in DNA replication.	0.998
ACPL_1392	ssb	ACPL_1392	ACPL_1290	DNA polymerase III, delta subunit.	Single-stranded DNA-binding protein.	0.745
ACPL_1659	ACPL_1392	ACPL_1659	ACPL_1392	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III, delta subunit.	0.961
ACPL_1659	ACPL_7611	ACPL_1659	ACPL_7611	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	Superfamily I DNA and RNA helicases.	0.890
ACPL_1659	ACPL_7634	ACPL_1659	ACPL_7634	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase sliding clamp subunit (PCNA homolog).	0.466
ACPL_1659	dnaE	ACPL_1659	ACPL_1740	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.527
ACPL_1659	dnaE-2	ACPL_1659	ACPL_1776	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III, alpha subunit.	0.950
ACPL_1659	dnaN	ACPL_1659	ACPL_117	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.940
ACPL_1659	dnaQ	ACPL_1659	ACPL_6692	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III, alpha subunit (gram-positive type).	0.983
ACPL_1659	dnaZ	ACPL_1659	ACPL_8134	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III, gamma/tau subunits.	0.949
ACPL_1659	holB	ACPL_1659	ACPL_496	DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.	DNA polymerase III subunit delta; ATPase involved in DNA replication.	0.958
ACPL_7611	ACPL_1392	ACPL_7611	ACPL_1392	Superfamily I DNA and RNA helicases.	DNA polymerase III, delta subunit.	0.867