Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_506Hypothetical protein. (575 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.910
ACPL_7611
Superfamily I DNA and RNA helicases.
  
 0.905
ACPL_7050
Nuclease sbcCD subunit C; Chromosome segregation ATPases.
 
 0.902
ACPL_1213
Chromosome partition protein smc; ATPase involved in DNA repair.
 
 0.899
ACPL_1100
Laminin subunit beta-2.
  
 0.879
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
 0.784
st2
Carbonic anhydrase; Sulfate permease and related transporters (MFS superfamily).
  
  0.716
dinG
Rad3-related DNA helicases.
   
 0.685
ACPL_2815
5'-3' exonuclease (including N-terminal domain of PolI).
   
 0.655
polA-2
DNA polymerase I; 5'-3' exonuclease (including N-terminal domain of PolI).
   
 0.655
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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