Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_5072Predicted transcriptional regulators. (246 aa)    
Predicted Functional Partners:
ACPL_5073
Oxoglutarate dehydrogenase inhibitor; FOG: FHA domain.
 
 
  0.903
ACPL_1164
Uncharacterized protein; 4-aminobutyrate aminotransferase and related aminotransferases.
  
    0.861
ACPL_5070
Predicted transcriptional regulators.
 
   
 0.755
ACPL_5071
Uncharacterized protein.
 
   
 0.735
ACPL_5075
Uncharacterized protein conserved in bacteria.
 
     0.643
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.567
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.511
ACPL_7057
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
  
   
 0.493
secG
Protein-export membrane protein secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
  
 0.470
ACPL_3017
Uncharacterized protein conserved in bacteria.
  
     0.461
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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