Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5076Uncharacterized conserved protein (small basic protein). (110 aa)    
Predicted Functional Partners:
ACPL_5077
Uncharacterized protein conserved in bacteria.
 
  
 0.986
ACPL_5075
Uncharacterized protein conserved in bacteria.
 
  
 0.949
ACPL_170
Uncharacterized protein conserved in bacteria.
 
  
 0.887
pgsA
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.871
ACPL_5109
yaaA-like uncharacterized protein.
   
    0.684
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.570
disA
DNA integrity scanning protein disA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
  
     0.540
cphA
Cyanophycin synthetase; D-alanine-D-alanine ligase and related ATP-grasp enzymes.
 
     0.520
ACPL_554
Hypothetical protein; Transcription regulator of the Arc/MetJ class.
  
     0.513
ACPL_5073
Oxoglutarate dehydrogenase inhibitor; FOG: FHA domain.
       0.480
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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