Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fixCDigeranylgeranylglycerophospholipid reductase 2; Dehydrogenases (flavoproteins). (392 aa)    
Predicted Functional Partners:
fixA
Protein fixA; Electron transfer flavoprotein, beta subunit.
  
 
 0.642
ybjJ
Inner membrane protein ybjJ; Permeases of the major facilitator superfamily.
       0.572
ACPL_7394
Protein fixB; Electron transfer flavoprotein, alpha subunit.
  
 
 0.543
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.530
ACPL_461
Hypothetical protein; Predicted transmembrane transcriptional regulator (anti-sigma factor).
   
  
 0.516
ACPL_7053
Hypothetical protein; Predicted transmembrane transcriptional regulator (anti-sigma factor).
   
  
 0.516
chlI-2
Mg-chelatase subunit ChlI.
 
  
 0.490
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.469
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.469
ACPL_459
Trans-hexaprenyltranstransferase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.414
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]