Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5128Putative signaling protein; FOG: GGDEF domain. (348 aa)    
Predicted Functional Partners:
ACPL_4813
Putative signaling protein; FOG: EAL domain.
 
  
 0.796
ACPL_7462
Diguanylate cyclase; Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
     0.754
ACPL_1150
y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
 0.746
ACPL_3239
Putative signaling protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
    0.717
ACPL_5601
Signaling protein ykoW; Predicted signal transduction protein containing sensor and EAL domains.
 
  
 0.695
ACPL_985
Putative signaling protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
   0.685
salY
Macrolide export ATP-binding/permease protein macB; ABC-type antimicrobial peptide transport system, permease component.
       0.652
ACPL_5131
Methionine import ATP-binding protein metN; ABC-type sugar transport systems, ATPase components.
       0.652
cusB
DNA-directed RNA polymerase subunit beta; Membrane-fusion protein.
       0.652
ACPL_6398
Putative signaling protein; FOG: EAL domain.
  
   0.650
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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