Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5139Methyl-accepting chemotaxis protein. (488 aa)    
Predicted Functional Partners:
ACPL_5140
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 0.986
frzF
Methylase of chemotaxis methyl-accepting proteins.
 
 0.968
cheB-5
Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.965
ACPL_7936
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 0.901
ACPL_5138
Chemotaxis signal transduction protein.
  
 0.900
cheA
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 0.900
ACPL_5136
Chemotaxis signal transduction protein.
  
 0.898
ACPL_2203
Chemotaxis signal transduction protein.
 
 0.887
ACPL_7935
Chemotaxis signal transduction protein.
 
 0.885
arcB-2
Multi-sensor signal transduction histidine kinase; Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 
 0.870
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.