STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheB-5Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (357 aa)    
Predicted Functional Partners:
ACPL_5140
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 
 0.996
cheA
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 0.992
ACPL_7936
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
 
 0.992
frzF
Methylase of chemotaxis methyl-accepting proteins.
 
  
 0.976
ACPL_5139
Methyl-accepting chemotaxis protein.
 
 
 0.966
ACPL_2203
Chemotaxis signal transduction protein.
 
 
 0.953
ACPL_7935
Chemotaxis signal transduction protein.
 
 
 0.952
cheW
Chemotaxis signal transduction protein.
 
 
 0.946
tas
Methyl-accepting chemotaxis protein.
 
 0.941
mcpA
Biofilm dispersion protein bdlA; FOG: PAS/PAC domain.
 
 0.938
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.