Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5190Hypothetical protein. (185 aa)    
Predicted Functional Partners:
ftsE
Methionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division.
  
 0.972
fepC
Iron complex transport system ATP-binding protein; ABC-type oligopeptide transport system, ATPase component.
       0.752
fepD
Vitamin B12 import system permease protein btuC; ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.670
fepG
Vitamin B12 import system permease protein btuC; ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.670
ACPL_2838
Hypothetical protein.
   
 
 0.574
ACPL_7707
Hypothetical protein.
   
 
 0.574
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 0.540
rodA
Bacterial cell division membrane protein; Belongs to the SEDS family.
  
 
 0.531
ftsW
Bacterial cell division membrane protein; Belongs to the SEDS family.
  
 
 0.531
ACPL_934
Septum formation initiator protein.
     
 0.526
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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