Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_5196Membrane-bound protein lytR; Transcriptional regulator. (369 aa)    
Predicted Functional Partners:
mprA
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
    0.572
ACPL_5192
Two-component system, OmpR family, sensor histidine kinase MprB; Signal transduction histidine kinase.
 
     0.551
ACPL_5195
Respiratory burst oxidase-like protein; Predicted ferric reductase.
       0.536
ACPL_5194
Uncharacterized protein conserved in bacteria.
       0.533
rodA
Bacterial cell division membrane protein; Belongs to the SEDS family.
  
  
 0.510
ACPL_1390
ComE operon protein 1; Transcriptional accessory protein.
 
     0.503
nusG
Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
  
     0.483
ACPL_720
Protein Daple; Type V secretory pathway, adhesin AidA.
  
     0.428
ACPL_8116
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
  
     0.420
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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