Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5221Hypothetical protein. (276 aa)    
Predicted Functional Partners:
ACPL_5220
Hypothetical protein.
  
   0.865
ACPL_379
Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 
 0.745
glgB
1,4-alpha-glucan branching enzyme.
  
    0.708
ACPL_2444
Hypothetical protein; Signal transduction histidine kinase.
  
     0.674
ACPL_8151
Protein of unknown function DUF742; Predicted nucleoside-diphosphate sugar epimerases.
  
     0.660
ACPL_699
Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
   0.645
ACPL_5453
Transcriptional regulator.
  
     0.631
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
  
 0.630
ACPL_4387
Hypothetical protein.
  
     0.628
ACPL_2318
Signal transduction histidine kinase.
  
  
 0.625
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (8%) [HD]