ACPL_5245 protein (Actinoplanes sp. SE50110)

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Predicted Interactions

gene neighborhood

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textmining

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Score

ACPL_5245

Hypothetical protein. (505 aa)

Predicted Functional Partners:

pup

0.949

arc

0.947

prcA

0.930

prcB

0.928

ACPL_8311

0.677

wcnA

0.625

ACPL_1534

0.601

fdxG

0.593

hlyX

0.581

ACPL_527

0.539

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1534	ACPL_5245	ACPL_1534	ACPL_5245	Uncharacterized protein.	Hypothetical protein.	0.601
ACPL_1534	arc	ACPL_1534	ACPL_5247	Uncharacterized protein.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.488
ACPL_1534	hlyX	ACPL_1534	ACPL_8104	Uncharacterized protein.	Regulatory protein hlyX; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.	0.652
ACPL_5245	ACPL_1534	ACPL_5245	ACPL_1534	Hypothetical protein.	Uncharacterized protein.	0.601
ACPL_5245	ACPL_527	ACPL_5245	ACPL_527	Hypothetical protein.	Hypothetical protein; DNA or RNA helicases of superfamily II.	0.539
ACPL_5245	ACPL_8311	ACPL_5245	ACPL_8311	Hypothetical protein.	Uncharacterized protein.	0.677
ACPL_5245	arc	ACPL_5245	ACPL_5247	Hypothetical protein.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.947
ACPL_5245	fdxG	ACPL_5245	ACPL_5248	Hypothetical protein.	Ferredoxin.	0.593
ACPL_5245	hlyX	ACPL_5245	ACPL_8104	Hypothetical protein.	Regulatory protein hlyX; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.	0.581
ACPL_5245	prcA	ACPL_5245	ACPL_5242	Hypothetical protein.	Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.930
ACPL_5245	prcB	ACPL_5245	ACPL_5243	Hypothetical protein.	Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.928
ACPL_5245	pup	ACPL_5245	ACPL_5244	Hypothetical protein.	Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.	0.949
ACPL_5245	wcnA	ACPL_5245	ACPL_5246	Hypothetical protein.	Putative peptidoglycan O-acetyltransferase yrhL; Predicted acyltransferases.	0.625
ACPL_527	ACPL_5245	ACPL_527	ACPL_5245	Hypothetical protein; DNA or RNA helicases of superfamily II.	Hypothetical protein.	0.539
ACPL_8311	ACPL_5245	ACPL_8311	ACPL_5245	Uncharacterized protein.	Hypothetical protein.	0.677
ACPL_8311	arc	ACPL_8311	ACPL_5247	Uncharacterized protein.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.832
ACPL_8311	prcA	ACPL_8311	ACPL_5242	Uncharacterized protein.	Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.975
ACPL_8311	prcB	ACPL_8311	ACPL_5243	Uncharacterized protein.	Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.973
ACPL_8311	pup	ACPL_8311	ACPL_5244	Uncharacterized protein.	Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.	0.726
arc	ACPL_1534	ACPL_5247	ACPL_1534	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	Uncharacterized protein.	0.488