STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yclJyclJ-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (184 aa)    
Predicted Functional Partners:
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
 
 0.932
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.922
ACPL_5292
Hypothetical protein; Panthothenate kinase.
       0.783
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
 
 0.771
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
  
 
 0.754
ACPL_2260
Sensor histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.725
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
 
 
 0.704
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.698
ACPL_3741
Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
     0.678
tcsA-2
PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase.
  
 
 0.660
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.