STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chlI-2Mg-chelatase subunit ChlI. (701 aa)    
Predicted Functional Partners:
hemG
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.960
cobN
Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
 
 0.958
chlI
Mg-chelatase subunit ChlI.
  
 0.948
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.945
cobI
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Precorrin-3B methylase.
 
   
 0.893
cobL
precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Precorrin-6B methylase 1.
 
   
 0.892
btuR
ATP:corrinoid adenosyltransferase.
 
   
 0.891
cobE
Protein cobE; Cobalamin biosynthesis protein CbiG.
 
   
 0.880
cobB-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
   
 0.875
cobB
Cobyrinic acid a,c-diamide synthase.
 
   
 0.796
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.