ACPL_5314 protein (Actinoplanes sp. SE50110)

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Score

ACPL_5314

Methionine synthase I, cobalamin-binding domain. (418 aa)

Predicted Functional Partners:

ACPL_5313

0.884

ACPL_2803

0.736

metH

0.676

ACPL_1247

0.592

folD

0.553

ACPL_1709

0.545

ACPL_4649

0.545

gcvP

0.505

deoC

0.505

deoC-2

0.505

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1247	ACPL_5314	ACPL_1247	ACPL_5314	Putative secreted protein.	Methionine synthase I, cobalamin-binding domain.	0.592
ACPL_1709	ACPL_5314	ACPL_1709	ACPL_5314	5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase I, cobalamin-binding domain.	0.545
ACPL_1709	folD	ACPL_1709	ACPL_7100	5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.951
ACPL_1709	gcvP	ACPL_1709	ACPL_4412	5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.777
ACPL_1709	metH	ACPL_1709	ACPL_1947	5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.997
ACPL_2803	ACPL_5314	ACPL_2803	ACPL_5314	Beta-lysine 5,6-aminomutase.	Methionine synthase I, cobalamin-binding domain.	0.736
ACPL_4649	ACPL_5313	ACPL_4649	ACPL_5313	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	Serine phosphatase RsbU, regulator of sigma subunit.	0.474
ACPL_4649	ACPL_5314	ACPL_4649	ACPL_5314	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	Methionine synthase I, cobalamin-binding domain.	0.545
ACPL_4649	gcvP	ACPL_4649	ACPL_4412	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.407
ACPL_5313	ACPL_4649	ACPL_5313	ACPL_4649	Serine phosphatase RsbU, regulator of sigma subunit.	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.474
ACPL_5313	ACPL_5314	ACPL_5313	ACPL_5314	Serine phosphatase RsbU, regulator of sigma subunit.	Methionine synthase I, cobalamin-binding domain.	0.884
ACPL_5314	ACPL_1247	ACPL_5314	ACPL_1247	Methionine synthase I, cobalamin-binding domain.	Putative secreted protein.	0.592
ACPL_5314	ACPL_1709	ACPL_5314	ACPL_1709	Methionine synthase I, cobalamin-binding domain.	5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.545
ACPL_5314	ACPL_2803	ACPL_5314	ACPL_2803	Methionine synthase I, cobalamin-binding domain.	Beta-lysine 5,6-aminomutase.	0.736
ACPL_5314	ACPL_4649	ACPL_5314	ACPL_4649	Methionine synthase I, cobalamin-binding domain.	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.545
ACPL_5314	ACPL_5313	ACPL_5314	ACPL_5313	Methionine synthase I, cobalamin-binding domain.	Serine phosphatase RsbU, regulator of sigma subunit.	0.884
ACPL_5314	deoC	ACPL_5314	ACPL_653	Methionine synthase I, cobalamin-binding domain.	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.	0.505
ACPL_5314	deoC-2	ACPL_5314	ACPL_7754	Methionine synthase I, cobalamin-binding domain.	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.	0.505
ACPL_5314	folD	ACPL_5314	ACPL_7100	Methionine synthase I, cobalamin-binding domain.	Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.553
ACPL_5314	gcvP	ACPL_5314	ACPL_4412	Methionine synthase I, cobalamin-binding domain.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.505