Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_5319Membrane-bound protein lytR; Transcriptional regulator. (359 aa)    
Predicted Functional Partners:
nadR
Transcriptional regulator nadR; FAD synthase.
   
  
 0.712
ACPL_3915
Carbohydrate diacid regulator; Regulator of polyketide synthase expression.
   
    0.682
ACPL_1870
Predicted transcriptional regulator.
  
    0.651
sepF
Cell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
     0.650
ACPL_1390
ComE operon protein 1; Transcriptional accessory protein.
 
     0.637
afsR-2
Regulatory protein afsR; Predicted ATPase.
   
    0.636
ACPL_7632
Chromosome initiation inhibitor; Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
    0.632
hrpA
HrpA-like helicases.
       0.581
ACPL_2813
Transcriptional regulators.
   
    0.554
ACPL_2966
HTH-type transcriptional regulator betI; Uncharacterized protein conserved in bacteria.
   
    0.535
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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