Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppgKPolyphosphate glucokinase; Transcriptional regulator/sugar kinase. (283 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.934
ppgK-2
Polyphosphate glucokinase; Transcriptional regulator/sugar kinase.
  
  
 
0.922
pgmA
Phosphoglucomutase.
    
 0.915
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
    
 0.905
yihR
Aldose 1-epimerase; Galactose mutarotase and related enzymes.
    
 0.905
ACPL_2155
6-phospho-beta-glucosidase; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases.
    
 0.904
bglY
6-phospho-beta-glucosidase; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases.
    
 0.904
ACPL_1061
Glucosamine 6-phosphate synthetase; Contains amidotransferase and phosphosugar isomerase domains.
  
 
 0.903
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 
 
 0.873
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
  
 0.846
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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