Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5401Hypothetical protein; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (211 aa)    
Predicted Functional Partners:
ACPL_5400
Hypothetical protein.
       0.773
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
   
 0.621
ACPL_5399
Hypothetical protein; Hydrolases of the alpha/beta superfamily.
       0.550
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
   
 0.527
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
   
 0.527
ACPL_1076
Zinc finger and BTB domain-containing protein 17.
  
  
 0.525
ACPL_5398
Hypothetical protein.
       0.469
ACPL_6195
Polyketide synthase modules and related proteins.
  
 
 0.439
ppsC
Non-ribosomal peptide synthetase modules and related proteins.
    
 0.419
tycC
Non-ribosomal peptide synthetase modules and related proteins.
    
 0.410
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.