Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5407PfkB domain protein; Sugar kinases, ribokinase family. (353 aa)    
Predicted Functional Partners:
bglY
6-phospho-beta-glucosidase; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases.
 
     0.946
uspC
uspC-like extracellular binding protein; ABC-type sugar transport system, periplasmic component.
 
    0.820
uspB
uspB-like inner membrane ABC transporter permease protein; ABC-type sugar transport system, permease component.
  
    0.787
uspA
ABC-type sugar transport systems, permease components.
  
    0.785
iolB
5-deoxy-glucuronate isomerase; Uncharacterized enzyme involved in inositol metabolism.
 
  
 0.706
iolE
Inosose dehydratase; Sugar phosphate isomerases/epimerases.
 
  
 0.674
ACPL_5408
Hypothetical protein.
       0.645
iolD
3D-(3,5/4)-trihydroxycyclohexane-1, 2-dione hydrolase; Acetolactate synthase; Belongs to the TPP enzyme family.
 
  
 0.629
sodF
Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.617
ACPL_2155
6-phospho-beta-glucosidase; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases.
 
     0.554
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.