Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_5462Spermidine/putrescine import ATP-binding protein potA; ABC-type spermidine/putrescine transport systems, ATPase components. (240 aa)    
Predicted Functional Partners:
pdr1-3
Pleiotropic drug resistance protein 1; ABC-type multidrug transport system, permease component.
 
 0.987
ACPL_5460
Transcriptional regulator.
 
     0.755
ACPL_5463
Hypothetical protein; Predicted phosphoribosyltransferases.
 
     0.648
ACPL_619
Antibiotic transport system permease protein; Putative exporter of polyketide antibiotics.
 
 
 0.614
ACPL_620
Antibiotic transport system permease protein; Putative exporter of polyketide antibiotics.
 
 
 0.588
drrB
Daunorubicin resistance transmembrane protein; ABC-type multidrug transport system, permease component.
 
 
 0.586
pdr1-2
Pleiotropic drug resistance protein 1; ABC-type multidrug transport system, permease component.
 
 
 0.581
pdr1
Pleiotropic drug resistance protein 1; ABC-type multidrug transport system, permease component.
 
 
  0.579
ACPL_5464
Dienelactone hydrolase; Predicted phosphoribosyltransferases.
       0.578
ACPL_4557
ABC-type multidrug transport system, permease component.
 
 
 0.573
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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