Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_5466ANTAR domain protein with unknown sensor; Signal transduction protein containing GAF and PtsI domains. (235 aa)    
Predicted Functional Partners:
ACPL_2250
ANTAR domain protein with unknown sensor.
  
     0.758
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
  
 0.706
gltB
Glutamate synthase domain 2.
  
  
 0.617
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.576
ACPL_2318
Signal transduction histidine kinase.
  
  
 0.556
ACPL_6357
Polycystic kidney disease protein 1-like 3; Cation/multidrug efflux pump.
 
    0.514
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Uroporphyrinogen-III methylase.
  
  
 0.499
peg3
Paternally-expressed gene 3 protein.
  
     0.488
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
  
  
 0.485
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
  
  
 0.485
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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