Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_5471Sphingomyelin phosphodiesterase 2. (425 aa)    
Predicted Functional Partners:
ACPL_4823
Hypothetical protein.
  
     0.739
ACPL_400
Pectate lyase; Alpha-L-arabinofuranosidase.
  
  
  0.730
ACPL_5020
Pectate lyase.
 
     0.719
abfB-2
Arabinofuranosidase.
  
     0.607
ACPL_3005
Endoglucanase.
  
     0.604
ACPL_5472
Extracellular serine protease; Membrane-associated phospholipid phosphatase.
 
     0.603
ACPL_4840
Hypothetical protein.
  
     0.587
ACPL_6911
Collagen alpha-4(VI) chain; Secreted and surface protein containing fasciclin-like repeats.
  
   
 0.586
ACPL_5470
Predicted membrane protein.
       0.585
ACPL_1286
Hypothetical protein.
  
     0.572
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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