STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5472Extracellular serine protease; Membrane-associated phospholipid phosphatase. (605 aa)    
Predicted Functional Partners:
ACPL_5473
O-phthalyl amidase; Uncharacterized protein conserved in bacteria.
 
     0.617
ACPL_5471
Sphingomyelin phosphodiesterase 2.
 
     0.604
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
   
 0.565
ACPL_5470
Predicted membrane protein.
 
     0.527
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
   
 0.507
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
   
 0.507
ACPL_4770
Glycerol kinase; Sugar (pentulose and hexulose) kinases.
  
     0.488
ACPL_6193
Non-ribosomal peptide synthetase modules and related proteins.
   
 0.427
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.419
nrps1D
Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.409
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.