Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
putANAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (1114 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase domain 2.
  
 
 0.972
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
 0.948
ACPL_7532
Ornithine-oxo-acid transaminase; Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.948
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 0.940
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.938
gadB
Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.
   
 0.927
ACPL_2126
Acyl-CoA dehydrogenases.
  
 
 0.925
fadE-3
Acyl-CoA dehydrogenases.
  
 
 0.925
fadE-4
Acyl-CoA dehydrogenases.
  
 
 0.925
acd-3
Acyl-CoA dehydrogenases.
  
 
 0.925
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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