STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsHPhosphotransferase system, HPr-related proteins. (86 aa)    
Predicted Functional Partners:
ptsI
Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.994
ACPL_5469
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria).
  
 0.985
fruB
PTS system, mannitol-specific IIA component; Mannitol/fructose-specific phosphotransferase system, IIA domain.
 
 
 0.974
mtlA-2
Phosphotransferase system, mannitol-specific IIBC component.
 
 
 0.957
dhaL
Dihydroxyacetone kinase, C-terminal domain protein; Dihydroxyacetone kinase.
  
 
 0.955
dak1
Dihydroxyacetone kinase, N-terminal domain protein; Dihydroxyacetone kinase.
  
 
 0.955
hpr
Phosphotransferase system, HPr-related proteins.
 
  
 0.928
ACPL_5491
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Phosphotransferase system, mannose/fructose-specific component IIA.
 
   
 0.898
ACPL_6373
Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.727
rpsG
Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
 
    0.691
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.