STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5513FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Thioredoxin reductase. (521 aa)    
Predicted Functional Partners:
ACPL_5514
ydcN-like uncharacterized HTH-type transcriptional regulator; Predicted transcriptional regulators.
 
  
 0.781
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.743
coaE
dephospho-CoA kinase/unknown domain fusion protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.730
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
 
 0.701
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
 
 
 0.693
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.693
sat1
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
     
 0.635
paaK
Phenylacetic acid degradation NADH oxidoreductase; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
   
 
 0.628
ACPL_5396
Oxidoreductase FAD-binding domain protein; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
   
 
 0.628
ppsC
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.610
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.