Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_553NADPH-dependent oxidoreductase; Nitroreductase. (207 aa)    
Predicted Functional Partners:
yihR
Aldose 1-epimerase; Galactose mutarotase and related enzymes.
 
    0.830
pdxH-2
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  
  
 0.785
ACPL_551
Permeases of the major facilitator superfamily.
       0.766
ACPL_554
Hypothetical protein; Transcription regulator of the Arc/MetJ class.
       0.631
ACPL_555
Acyl-CoA dehydrogenases.
       0.546
ACPL_549
Citrate synthase; Belongs to the citrate synthase family.
  
    0.539
ACPL_548
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
     
 0.533
ACPL_6870
Pleiotropic drug resistance protein 3; ABC-type multidrug transport system, permease component.
 
    0.489
ACPL_608
Histidine kinase.
  
     0.463
ACPL_3403
Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases.
  
    0.457
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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