Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ACPL_554Hypothetical protein; Transcription regulator of the Arc/MetJ class. (98 aa)    
Predicted Functional Partners:
ACPL_555
Acyl-CoA dehydrogenases.
       0.741
yihR
Aldose 1-epimerase; Galactose mutarotase and related enzymes.
       0.724
pdxH-2
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.702
disA
DNA integrity scanning protein disA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
  
     0.691
ACPL_7391
Methionine synthase vitamin-B12 independent.
  
     0.641
ACPL_553
NADPH-dependent oxidoreductase; Nitroreductase.
       0.631
ACPL_556
Hypothetical protein.
       0.602
ACPL_551
Permeases of the major facilitator superfamily.
       0.592
ACPL_7776
yjcG-like uncharacterized protein; 2'-5' RNA ligase.
  
     0.583
ACPL_549
Citrate synthase; Belongs to the citrate synthase family.
 
     0.536
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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