STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_554Hypothetical protein; Transcription regulator of the Arc/MetJ class. (98 aa)    
Predicted Functional Partners:
ACPL_555
Acyl-CoA dehydrogenases.
       0.752
yihR
Aldose 1-epimerase; Galactose mutarotase and related enzymes.
       0.745
pdxH-2
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.723
disA
DNA integrity scanning protein disA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
  
     0.691
ACPL_7391
Methionine synthase vitamin-B12 independent.
  
     0.641
ACPL_553
NADPH-dependent oxidoreductase; Nitroreductase.
       0.632
ACPL_556
Hypothetical protein.
       0.618
ACPL_551
Permeases of the major facilitator superfamily.
       0.593
ACPL_7776
yjcG-like uncharacterized protein; 2'-5' RNA ligase.
  
     0.583
ACPL_549
Citrate synthase; Belongs to the citrate synthase family.
 
     0.536
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.