Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5552Hypothetical protein. (243 aa)    
Predicted Functional Partners:
ACPL_5551
Hypothetical protein.
 
     0.958
ACPL_5553
Hypothetical protein.
       0.773
ACPL_5554
Hypothetical protein.
       0.773
tcbF
Lactaldehyde reductase; Alcohol dehydrogenase, class IV.
  
    0.735
lexA-2
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.555
ACPL_2653
Putative 55.3 kDa protein in thcA 5'region; Glycosyltransferases involved in cell wall biogenesis.
  
    0.420
ccdA
Cytochrome c biogenesis protein.
   
    0.420
ACPL_4934
Hypothetical protein.
  
     0.400
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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