Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_5559Nuclease (SNase domain protein). (392 aa)    
Predicted Functional Partners:
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
 
 0.644
hrpA
HrpA-like helicases.
    
 0.557
ACPL_6614
ATP-dependent helicase HrpB; HrpA-like helicases.
    
 0.557
ACPL_5560
Lipid A export ATP-binding/permease protein msbA; ABC-type multidrug transport system, ATPase and permease components.
   
   0.544
ACPL_5561
Lipid A export ATP-binding/permease protein msbA; ABC-type multidrug transport system, ATPase and permease components.
   
   0.544
ddx5
DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases.
    
 0.529
deaD
Cold-shock DEAD box protein A; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
 0.529
ACPL_6666
Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.
    
 0.529
ACPL_717
Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
 0.529
ACPL_910
Membrane protein involved in the export of O-antigen and teichoic acid.
  
  
 0.452
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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