Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_5560Lipid A export ATP-binding/permease protein msbA; ABC-type multidrug transport system, ATPase and permease components. (589 aa)    
Predicted Functional Partners:
ACPL_5561
Lipid A export ATP-binding/permease protein msbA; ABC-type multidrug transport system, ATPase and permease components.
 
    
0.820
cydCD
Multidrug resistance protein 2; ABC-type multidrug transport system, ATPase and permease components.
  
 
  0.719
ACPL_4303
Ribose import ATP-binding protein rbsA; ATPase components of various ABC-type transport systems, contain duplicated ATPase.
  
 
 0.696
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.686
dnaK-3
Molecular chaperone.
 
 0.645
ACPL_6195
Polyketide synthase modules and related proteins.
  
 0.618
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.588
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.588
dnaK-4
Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.
  
  0.583
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.576
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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