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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5589Carotenoid cleavage dioxygenase; Lignostilbene-alpha,beta-dioxygenase and related enzymes. (447 aa)    
Predicted Functional Partners:
ACPL_5588
Hypothetical protein.
 
     0.757
egtD
Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
   
 0.698
ACPL_8205
Hypothetical protein.
    
 0.694
ACPL_5587
Predicted transcriptional regulators.
 
     0.632
purD
Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
   
  
 0.615
ACPL_4384
Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
      
 0.611
ACPL_5590
DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
       0.464
ACPL_5591
Hypothetical protein.
       0.464
ACPL_5592
Hypothetical protein.
       0.464
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.456
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.