STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_559Anti-sigma regulatory factor (Ser/Thr protein kinase). (158 aa)    
Predicted Functional Partners:
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
  
 0.630
ACPL_2318
Signal transduction histidine kinase.
  
  
 0.625
ACPL_1801
Polycystic kidney disease protein 1-like 3; Exoribonuclease R.
  
     0.617
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
  
 0.601
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.596
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
  
  
 0.593
ACPL_379
Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 
 0.583
ACPL_2108
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
   0.543
ACPL_7507
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
   0.543
ACPL_2445
Hypothetical protein; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
 
   0.542
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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