Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_5618Cell surface glycoprotein 1; Predicted drug exporters of the RND superfamily. (295 aa)    
Predicted Functional Partners:
ACPL_419
Polycystic kidney disease protein 1-like 3; Type V secretory pathway, adhesin AidA.
  
     0.557
ACPL_5296
Obscurin; Spore coat assembly protein.
  
     0.527
ACPL_1560
Mucin-19; Predicted membrane protein.
  
     0.501
nhaA
Na(+)/H(+) antiporter nhaA 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.498
ACPL_6979
Mucin 1-like protein; Cell surface associated.
  
     0.498
otsB
HAD family hydrolase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.498
ACPL_2881
Collagen alpha-5(VI) chain; Translation initiation factor 2 (IF-2; GTPase).
  
     0.495
ACPL_1736
Collagen alpha-5(VI) chain; FOG: Glucan-binding domain (YG repeat).
  
     0.468
ACPL_2000
Triple functional domain protein; Myosin heavy chain.
  
     0.455
ACPL_593
Translation initiation factor IF-2; DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
     0.437
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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