node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACPL_2486 | egtD | ACPL_2486 | ACPL_6424 | Hypothetical protein. | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.791 |
ACPL_2486 | gshA | ACPL_2486 | ACPL_2302 | Hypothetical protein. | Glutamate-cysteine ligase; Similar to chloroplast protein; Gamma-glutamylcysteine synthetase. | 0.523 |
ACPL_2486 | gshA-2 | ACPL_2486 | ACPL_6427 | Hypothetical protein. | Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.523 |
ACPL_3993 | egtB | ACPL_3993 | ACPL_6426 | Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Predicted glutamine amidotransferase. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.866 |
ACPL_3993 | egtD | ACPL_3993 | ACPL_6424 | Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Predicted glutamine amidotransferase. | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.793 |
ACPL_3993 | gshA | ACPL_3993 | ACPL_2302 | Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Predicted glutamine amidotransferase. | Glutamate-cysteine ligase; Similar to chloroplast protein; Gamma-glutamylcysteine synthetase. | 0.510 |
ACPL_3993 | gshA-2 | ACPL_3993 | ACPL_6427 | Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Predicted glutamine amidotransferase. | Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.591 |
ACPL_4384 | ACPL_5589 | ACPL_4384 | ACPL_5589 | Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain). | Carotenoid cleavage dioxygenase; Lignostilbene-alpha,beta-dioxygenase and related enzymes. | 0.611 |
ACPL_4384 | egtD | ACPL_4384 | ACPL_6424 | Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain). | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.675 |
ACPL_5589 | ACPL_4384 | ACPL_5589 | ACPL_4384 | Carotenoid cleavage dioxygenase; Lignostilbene-alpha,beta-dioxygenase and related enzymes. | Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain). | 0.611 |
ACPL_5589 | egtD | ACPL_5589 | ACPL_6424 | Carotenoid cleavage dioxygenase; Lignostilbene-alpha,beta-dioxygenase and related enzymes. | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.698 |
cbiN | egtB | ACPL_6425 | ACPL_6426 | Putative glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.998 |
cbiN | egtD | ACPL_6425 | ACPL_6424 | Putative glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.986 |
cbiN | gshA | ACPL_6425 | ACPL_2302 | Putative glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Glutamate-cysteine ligase; Similar to chloroplast protein; Gamma-glutamylcysteine synthetase. | 0.719 |
cbiN | gshA-2 | ACPL_6425 | ACPL_6427 | Putative glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.955 |
egtB | ACPL_3993 | ACPL_6426 | ACPL_3993 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Predicted glutamine amidotransferase. | 0.866 |
egtB | cbiN | ACPL_6426 | ACPL_6425 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Putative glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.998 |
egtB | egtD | ACPL_6426 | ACPL_6424 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.999 |
egtB | gshA | ACPL_6426 | ACPL_2302 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamate-cysteine ligase; Similar to chloroplast protein; Gamma-glutamylcysteine synthetase. | 0.903 |
egtB | gshA-2 | ACPL_6426 | ACPL_6427 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.981 |