STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_674Transcriptional repressor mprA; Transcriptional regulators. (157 aa)    
Predicted Functional Partners:
ribA-3
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
       0.793
ACPL_675
CMP/dCMP deaminase zinc-binding protein; Pyrimidine deaminase.
       0.773
ACPL_7595
Transcriptional regulators.
  
     0.628
ACPL_7117
Uncharacterized protein; DNA or RNA helicases of superfamily II.
  
     0.496
ACPL_677
Putative cellulose synthase A catalytic subunit 2; UDP-forming; Glycosyltransferases, probably involved in cell wall biogenesis.
  
    0.491
ACPL_1960
Uncharacterized protein; Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.
  
     0.488
ctaA
Heme A synthase; Uncharacterized protein required for cytochrome oxidase assembly.
  
     0.448
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.