STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimKLysine biosynthesis protein LysX; Biotin carboxylase; Belongs to the RimK family. (288 aa)    
Predicted Functional Partners:
ACPL_4302
Putative transcriptional regulator, GntR family; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.
     
  0.900
ACPL_8270
Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.
     
  0.900
ACPL_8375
Putative aminotransferase; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.
     
  0.900
lysK
Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
 
   
 0.895
ACPL_7492
Hypothetical protein; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis.
  
    0.858
ACPL_7494
Hypothetical protein.
       0.835
tktC
Transketolase; Deoxyxylulose-5-phosphate synthase.
  
    0.793
ACPL_7488
Transketolase, N-terminal subunit.
  
    0.790
argC-2
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.765
ACPL_7491
Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
  
    0.765
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.