| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EPR76017.1 | EPR77235.1 | ADILRU_1534 | ADILRU_0344 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 0.560 |
| EPR76017.1 | coaA | ADILRU_1534 | ADILRU_1247 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase. | 0.948 |
| EPR76017.1 | coaD | ADILRU_1534 | ADILRU_0629 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.970 |
| EPR76017.1 | coaE | ADILRU_1534 | ADILRU_2220 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.885 |
| EPR76017.1 | ispDF | ADILRU_1534 | ADILRU_1432 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.485 |
| EPR76788.1 | EPR76789.1 | ADILRU_0627 | ADILRU_0628 | 16S rRNA (guanine(966)-N(2))-methyltransferase. | ATP-dependent DNA helicase RecG. | 0.666 |
| EPR76788.1 | coaD | ADILRU_0627 | ADILRU_0629 | 16S rRNA (guanine(966)-N(2))-methyltransferase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.933 |
| EPR76789.1 | EPR76788.1 | ADILRU_0628 | ADILRU_0627 | ATP-dependent DNA helicase RecG. | 16S rRNA (guanine(966)-N(2))-methyltransferase. | 0.666 |
| EPR76789.1 | coaD | ADILRU_0628 | ADILRU_0629 | ATP-dependent DNA helicase RecG. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.677 |
| EPR76789.1 | fgd | ADILRU_0628 | ADILRU_0630 | ATP-dependent DNA helicase RecG. | F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. | 0.461 |
| EPR77235.1 | EPR76017.1 | ADILRU_0344 | ADILRU_1534 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.560 |
| EPR77235.1 | coaD | ADILRU_0344 | ADILRU_0629 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.736 |
| EPR77235.1 | coaE | ADILRU_0344 | ADILRU_2220 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.482 |
| EPR77235.1 | guaA | ADILRU_0344 | ADILRU_1275 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.445 |
| EPR77235.1 | ispDF | ADILRU_0344 | ADILRU_1432 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.702 |
| coaA | EPR76017.1 | ADILRU_1247 | ADILRU_1534 | Pantothenate kinase. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.948 |
| coaA | coaD | ADILRU_1247 | ADILRU_0629 | Pantothenate kinase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.905 |
| coaD | EPR76017.1 | ADILRU_0629 | ADILRU_1534 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.970 |
| coaD | EPR76788.1 | ADILRU_0629 | ADILRU_0627 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 16S rRNA (guanine(966)-N(2))-methyltransferase. | 0.933 |
| coaD | EPR76789.1 | ADILRU_0629 | ADILRU_0628 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | ATP-dependent DNA helicase RecG. | 0.677 |