| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EPR75016.1 | EPR75017.1 | ADILRU_2690 | ADILRU_2691 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.998 |
| EPR75016.1 | EPR75935.1 | ADILRU_2690 | ADILRU_1781 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component. | 0.683 |
| EPR75016.1 | EPR76105.1 | ADILRU_2690 | ADILRU_1622 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase. | 0.778 |
| EPR75016.1 | EPR76192.1 | ADILRU_2690 | ADILRU_1523 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Putative ferredoxin containing dehydrogenase. | 0.727 |
| EPR75016.1 | folD | ADILRU_2690 | ADILRU_1396 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.866 |
| EPR75016.1 | gcvH | ADILRU_2690 | ADILRU_1875 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
| EPR75016.1 | gcvP | ADILRU_2690 | ADILRU_1876 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.988 |
| EPR75016.1 | gcvT | ADILRU_2690 | ADILRU_1874 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. | 0.997 |
| EPR75016.1 | glyA | ADILRU_2690 | ADILRU_1395 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| EPR75017.1 | EPR75016.1 | ADILRU_2691 | ADILRU_2690 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | 0.998 |
| EPR75017.1 | EPR75935.1 | ADILRU_2691 | ADILRU_1781 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component. | 0.638 |
| EPR75017.1 | EPR76105.1 | ADILRU_2691 | ADILRU_1622 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase. | 0.845 |
| EPR75017.1 | EPR76192.1 | ADILRU_2691 | ADILRU_1523 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative ferredoxin containing dehydrogenase. | 0.727 |
| EPR75017.1 | folD | ADILRU_2691 | ADILRU_1396 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.791 |
| EPR75017.1 | gcvH | ADILRU_2691 | ADILRU_1875 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.994 |
| EPR75017.1 | gcvP | ADILRU_2691 | ADILRU_1876 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.977 |
| EPR75017.1 | gcvT | ADILRU_2691 | ADILRU_1874 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. | 0.997 |
| EPR75017.1 | glyA | ADILRU_2691 | ADILRU_1395 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.859 |
| EPR75935.1 | EPR75016.1 | ADILRU_1781 | ADILRU_2690 | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). | 0.683 |
| EPR75935.1 | EPR75017.1 | ADILRU_1781 | ADILRU_2691 | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component. | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.638 |
