Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EPR75754.1ATP-dependent DNA helicase; Overlaps another CDS with the same product name; Belongs to the helicase family. UvrD subfamily. (1089 aa)    
Predicted Functional Partners:
EPR75753.1
ATP-dependent DNA helicase; Overlaps another CDS with the same product name.
 
  
 0.995
EPR75132.1
Putative helicase.
  
 0.971
EPR75759.1
ATP-dependent DNA helicase UvrD/PcrA.
 
  
0.919
EPR76514.1
ATP-dependent DNA helicase UvrD/PcrA.
 
  
0.913
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.907
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.876
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
 0.841
lexA
SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.828
EPR75642.1
DNA polymerase III, epsilon subunit.
    
 0.814
EPR76588.1
UTP--glucose-1-phosphate uridylyltransferase.
     
  0.802
Your Current Organism:
Leifsonia rubra
NCBI taxonomy Id: 1348338
Other names: L. rubra CMS 76R, Leifsonia rubra CMS 76R
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