Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPR75770.1Glutamine synthetase family protein. (448 aa)    
Predicted Functional Partners:
EPR74999.1
Glutamate synthase [NADPH] large chain.
  
 
 0.970
EPR75000.1
Glutamate synthase [NADPH] small chain.
  
 
 0.855
EPR76111.1
Glutamine synthetase type I.
  
  
 
0.785
EPR76115.1
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.785
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.765
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
  
 0.755
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.743
EPR75374.1
Proline dehydrogenase (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase.
   
 
 0.743
gcvP
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.740
EPR75730.1
Glutamate decarboxylase.
     
 0.737
Your Current Organism:
Leifsonia rubra
NCBI taxonomy Id: 1348338
Other names: L. rubra CMS 76R, Leifsonia rubra CMS 76R
Server load: low (30%) [HD]