Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPR75497.1Threonine dehydratase. (375 aa)    
Predicted Functional Partners:
EPR75485.1
Aminotransferase, class III.
  
 
 0.809
EPR77646.1
Branched-chain amino acid aminotransferase.
  
 0.802
EPR77637.1
Acetolactate synthase large subunit.
  
 0.801
EPR77638.1
Acetolactate synthase small subunit.
  
 0.784
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.766
EPR75899.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.750
EPR75944.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.742
EPR74999.1
Glutamate synthase [NADPH] large chain.
  
 
 0.739
EPR77344.1
Low-specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
  
 
 0.727
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.717
Your Current Organism:
Leifsonia rubra
NCBI taxonomy Id: 1348338
Other names: L. rubra CMS 76R, Leifsonia rubra CMS 76R
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.