STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHN29094.1Mechanosensitive ion channel. (416 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.700
SHN39914.1
Amino acid/amide ABC transporter membrane protein 1, HAAT family /amino acid/amide ABC transporter membrane protein 2, HAAT family /amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; Belongs to the binding-protein-dependent transport system permease family.
    
  0.647
SHN45253.1
ABC-type branched-chain amino acid transport system, ATPase component; Belongs to the binding-protein-dependent transport system permease family.
    
  0.647
SHM64075.1
Branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.
    
  0.639
SHN16755.1
Branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.
    
  0.639
SHN75724.1
ABC-type branched-chain amino acid transport system, ATPase component; Belongs to the binding-protein-dependent transport system permease family.
    
  0.639
SHN29084.1
Hypothetical protein.
       0.615
SHN29101.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.586
SHN29119.1
Lysophospholipase L1.
     
 0.580
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.568
Your Current Organism:
Cryptosporangium aurantiacum
NCBI taxonomy Id: 134849
Other names: Actinoplanes aurantiacus, C. aurantiacum, DSM 46144, IFO 13967, IMET 9261, IMSNU 22120, JCM 3241, KCC A-0241, KCTC 9529, NBRC 13967, NCIMB 12649, NRRL B-16698, strain 71-C38
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.