STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC90676.1Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)    
Predicted Functional Partners:
KIC90268.1
Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.955
KIC96122.1
Chromosome segregation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.954
KIC95706.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.953
KIC95690.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.861
KIC95588.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.849
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.693
KIC94487.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.664
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.627
KIC94805.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.602
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.601
Your Current Organism:
Flavihumibacter solisilvae
NCBI taxonomy Id: 1349421
Other names: F. solisilvae, Flavihumibacter solisilvae Lee et al. 2014 emend. Hahnke et al. 2016, Flavihumibacter sp. 3_3, JCM 19891, KACC 17917, strain 3-3, strain 3_3
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