Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
hsdR_2Deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1049 aa)    
Predicted Functional Partners:
HsdM
Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
AOM14781.1
Restriction endonuclease subunit S; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
AOM17342.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.649
AOM17096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.539
AOM14783.1
Type II restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.521
AOM14784.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.521
mrnC
Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
      
 0.401
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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